Helena Ikonomidis Sackey

Publications
CV
Public outreach and news

Articles

Article: JOURNAL OF SEXUAL MEDICINE. 2026;23(2):qdaf379
Response to Letter to the Editor on "Improved health-related quality of life and gender congruence after gender-affirming mastectomy-a prospective cohort study"
Gran I; Dhejne C; Sackey H
Journal article: SCANDINAVIAN JOURNAL OF SURGERY. 2025;:14574969251407221
Gender-affirming surgery in the Nordic countries-advancing equitable, evidence-based care
Gran I; Mikkola A; Sackey H; Sommar P
Article: EJSO. 2025;51(12):110484
Local management of second breast cancer event after primary breast conserving therapy: The patient's perspective
Hannoun-Levi J-M; Margenthaler J; Anderson B; Di Micco R; Arthur D; Aznar M; Berry MP; Brown T; Burke E; De Boniface J; Dietz J; Dodwell D; Fredriksson I; Gentilini OD; Guix B; Gutierrez C; Haidinger R; Heditsian D; Kothari A; Lestage B; Lyons J; Mclean YF; Mackenzie M; Meattini I; Montero-Luis A; Mourtada F; Nguyen T; Petitti L; Polgar C; Poortmans P; Rocco N; Sackey H; Sarantou T; Showalter S; Strnad V; Kuehn T; Volders J; Peeters M-JV; Yashar C; Rubio IT; Gahm J; Zeidan Y; Kaidar-Person O; Dirbas FM
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112(12):znaf233
Major systemic infection following breast cancer surgery and oncological outcomes
Adwall L; Fredriksson I; Hultin H; Stalberg P; Mani M; Norlen O; Sackey H
Article: JOURNAL OF SEXUAL MEDICINE. 2025;22(10):1882-1890
Improved health-related quality of life and gender congruence after gender-affirming mastectomy-a prospective cohort study
Gran I; Kamali A; Granath F; Frisen L; Lindqvist EK; Dhejne C; Sommar P; Sackey H
Article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112(9):znaf180
Axillary dissection for low-volume nodal involvement after neoadjuvant therapy in breast cancer: multicentre AXSANA cohort study
Kuehn T; Banys-Paluchowski M; Ditsch N; Stickeler E; Hauptmann M; Schroth J; Karadeniz Cakmak G; Hahn M; Thill M; Reimer T; Froehlich S; Schmidt E; Wihlfahrt K; Berger T; Basali T; Ruf F; Rief A; Lux MP; Kolberg H-C; Rubio IT; Gasparri ML; Kontos M; Bonci E-A; Niinikoski L; Murawa D; Pinto D; Peintinger F; Schlichting E; Nina H; Valiyeva Qanimat H; Vanhoeij M; Rebaza LP; Aktas Sezen B; Jursik K; Kadayaprath G; Dostalek L; Kothari A; Perhavec A; Ivanov T; Zippel D; Thongvitokomarn S; Gurleyik MG; Watermann D; Porpiglia M; Lebeau A; Di Micco R; Gentilini OD; de Boniface J; Hartmann S
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.040-xi11
Long-term oncological outcomes after nipple-sparing mastectomy and implant-based immediate breast reconstruction in a large population-based cohort
Sackey H; Oikonomou I; Liu Y; Ansarei D; Halle M; Johansson ALV; de Boniface J
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.023-xi7
Impact of prior radiotherapy and implant-based reconstruction on microvascular outcome in DIEP flap breast reconstruction
Liu Y; Rittri S; Johansson ALV; Nord AE; Sackey H; de Boniface J; Halle M
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.024-xi7
Major systemic infection following breast cancer surgery associated with worse oncological outcomes
Adwall L; Fredriksson I; Hultin H; Stalberg P; Mani M; Norlen O; Sackey H
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.021-xi6
Effectiveness of incisional negative pressure wound therapy vs. standard dressings in breast surgery: a systematic review and meta-analysis
Kollatos C; Sackey H; Ohrn C; Valachis A; Eriksson S; Karakatsanis A
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.027
Impact of axillary staging after neoadjuvant chemotherapy for breast cancer on arm morbidity: one-year results from the AXSANA cohort study
Appelgren M; Sackey H; Lundholm C; Wengstrom Y; Hartmann S; Wihlfahrt K; Banys-Paluchowski M; Kuehn T; de Boniface J
Article: BREAST. 2025;82:104491
Phyllodes tumors of the breast: Real world data from a multi-institution cohort
Sars C; Frisell J; Dickman PW; de Flon FH; Karlsson F; Sackey H; Lindqvist EK
Journal article: SYSTEMATIC REVIEWS. 2025;14(1):142
Local recurrence of phyllodes tumors after surgery with wide compared to narrow margins: study protocol for a systematic review and meta-analysis
Sars C; Frisell J; Dickman PW; Sackey H; Lindqvist EK
Article: JOURNAL OF ADVANCED NURSING. 2025;81(6):3156-3165
'Balancing Challenges and Personal Resources': A Qualitative Study of Women's Experiences of Arm Impairment After Axillary Surgery for Breast Cancer
Appelgren M; Wengstroem Y; de Boniface J; Sackey H
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112(5):znaf031
Three-year patient-reported outcomes of the BOOG 2013-08 RCT evaluating omission of sentinel lymph node biopsy in early-stage breast cancer patients treated with breast conserving surgery: Impact of personality traits on health-related quality of life.
Wintraecken VM; van Roozendaal LM; Simons JM; de Vries J; van Kuijk SMJ; Vane MLG; van Dalen T; Sackey H; van der Hage JA; Strobbe LJA; Linn SC; Lobbes MBI; Poortmans PMP; Tjan-Heijnen VCG; van de Vijver KKBT; Westenberg HH; Dirksen CD; de Wilt JHW; Boersma LJ; Smidt ML
Journal article: EJSO. 2024;50:108848
Postoperative systemic infection after breast cancer surgery associated with increased risk for local recurrence
Adwall L; Fredriksson I; Hultin H; Mani M; Norlén O; Sackey H
Article: LANCET REGIONAL HEALTH-EUROPE. 2024;47:101083
Axillary clearance and chemotherapy rates in ER+HER2- breast cancer: secondary analysis of the SENOMAC trial
Tvedskov TF; Szulkin R; Alkner S; Andersson Y; Bergkvist L; Frisell J; Gentilini OD; Kontos M; Kuehn T; Lundstedt D; Offersen BV; Bagge RO; Reimer T; Sund M; Ryden L; Christiansen P; de Boniface J
Article: BJS OPEN. 2024;8(5):zrae095
Surgical complications after immediate implant-based breast reconstruction for breast cancer in women over 65 years
Liu Y; Johansson ALV; Oikonomou I; Frisell A; Adam HC; Ansarei D; Halle M; Sackey H; de Boniface J
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2024;111:znae175.024
Phyllodes Tumours: Interdisciplinary Management Recommendations from the Stockholm Region
Lindqvist E; Fahlen M; Fredholm H; Hartman J; Karlsson F; Papakonstantinou A; Sackey H; Zouzos A
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2024;111:znae175.023
Surgical complications after immediate implant-based breast reconstruction for breast cancer in women ≥ 65 years of age
Liu Y; Johansson ALV; Oikonomou I; Frisell A; Adam HC; Ansarei D; Halle M; Sackey H; de Boniface J
Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2024;111:znae175.112
The role of previous implant-based breast reconstruction and radiotherapy for surgical complications in DIEP breast reconstruction
Liu Y; Jakobsson S; Edsander-Nord A; Johansson ALV; Sackey H; de Boniface J; Halle M
Article: JPRAS OPEN. 2024;40:19-31
Complications after breast augmentation with dermal fillers containing copolyamide: A systematic review
Hedstrom K; Falk-Delgado A; Sackey H
Journal article: SENOLOGIE - ZEITSCHRIFT FÜR MAMMADIAGNOSTIK UND -THERAPIE. 2024;21(02):e27
Marking of Target Lymph Nodes with carbon suspension in breast cancer patients undergoing neoadjuvant chemotherapy – first results from the AXSANA study (NCT04373655)
Rief A; Hartmann S; Banys-Paluchowski M; de Boniface J; Gentlini OD; Stickeler E; Cakmak GK; Hauptmann M; Basali T; Berger T; Fröhlich S; Ruf F; Schmidt E; Wihlfahrt K; Sezen BA; Porpiglia M; Zetterlund L; Natsiopoulos I; Sackey H; Hadar T; Weigel M; Dostalek L; Iosifidou R; Schrauder MG; Kaltenecker G; Langanke D; Zippel D; Kühn T
Journal article: CANCER RESEARCH. 2024;84(9):po1-19-03-po1-19-03
The T-REX trial: a randomized international noninferiority trial on Tailored Regional EXternal beam radiotherapy in clinically node-negative breast cancer patients with 1-2 sentinel node macrometastases
Alkner S; de Boniface J; Lundstedt D; Mjaaland I; Ryden L; Vikstrom J; Bendahl P-O; Holmberg E; Sackey H; Wieslander E; Karlsson P
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2024;390(13):1163-1175
Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases
de Boniface J; Filtenborg Tvedskov T; Ryden L; Szulkin R; Reimer T; Kuehn T; Kontos M; Gentilini OD; Olofsson Bagge R; Sund M; Lundstedt D; Appelgren M; Ahlgren J; Norenstedt S; Celebioglu F; Sackey H; Scheel Andersen I; Hoyer U; Nyman PF; Vikhe Patil E; Wieslander E; Dahl Nissen H; Alkner S; Andersson Y; Offersen BV; Bergkvist L; Frisell J; Christiansen P
Journal article: EUROPEAN JOURNAL OF CANCER. 2024;200:113675
The impact of personality traits on health-related quality of life in cT12N0 breast cancer patients treated with breast-conserving therapy: Three years patient-reported outcomes of the BOOG 2013-08 randomized controlled trial
Wintraecken V; van Roozendaal L; Simons J; de Vries J; van Kuijk S; Sackey H; Vane M; van Dalen T; van der Hage J; Strobbe L; Linn S; Lobbes M; Poortmans P; Tjan-Heijnen V; van der Vijver K; Westenberg H; Dirksen C; de Wilt H; Boersma L; Smidt M
Journal article: EJSO. 2024;50(2):107581
Phyllodes tumors and Breast Sarcoma: Real World Data from a Multi-Institution Cohort
Sars C; Sackey H; Frisell J; Dickman P; Lindqvist E
Journal article: EJSO. 2024;50(2):107446
Patients’ experiences of axillary surgery in the randomized SENOMAC trial: a focus group study
Appelgren M; Wengström Y; de Boniface J; Sackey H
Journal article: EJSO. 2024;50(2):107402
Current Clinical Practice in the Management of Sarcomas of the Breast: An International Cross-Sectional Study among Surgeons and Oncologists
Sars C; Sackey H; Lindqvist E
Article: CLINICAL ONCOLOGY. 2024;36(1):e31-e39
Multidisciplinary Management of Phyllodes Tumours and Breast Sarcoma: A Cross-sectional Survey of Clinical Practice across the UK
Bishr MK; Banks J; Abdelaziz MS; Badawi M; Crane PW; Donigiewicz UJ; Elkorety M; Girgis M; Humphreys A; Isherwood J; Kahan J; Keelan S; Lindqvist EK; Nixon I; Sackey H; Sars C; Soliman H; Touqan N; Remoundos DD; Ahmed M
Article: BMJ OPEN. 2023;13(9):e075543
Protocol for the T-REX-trial: tailored regional external beam radiotherapy in clinically node-negative breast cancer patients with 1-2 sentinel node macrometastases - an open, multicentre, randomised non-inferiority phase 3 trial
Alkner S; de Boniface J; Lundstedt D; Mjaaland I; Ryden L; Vikstrom J; Bendahl P-O; Holmberg E; Sackey H; Wieslander E; Karlsson P
Article: BREAST CANCER RESEARCH AND TREATMENT. 2023;199(2):293-304
Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists
Sars C; Sackey H; Frisell J; Dickman PW; Karlsson F; Kindts I; Marta GN; Freitas-Junior R; Tvedskov TF; Kassem L; Ali AS; Ihalainen H; Neron M; Kontos M; Kaidar-Person O; Meattini I; Francken AB; van Duijnhoven F; Moberg IO; Marinko T; Kollar A; Ahmed M; Remoundos D; Banks J; Jagsi R; Dossett LA; Lindqvist EK
Article: PLASTIC AND RECONSTRUCTIVE SURGERY - GLOBAL OPEN. 2022;10(11):e4645
Implant Attributes or Patient Characteristics? Factors Affecting Outcome after Breast Augmentation in Transgender Women
Kamali A; Sackey H; Gran I; Sigurjonsson H; Farnebo F; Lundgren K; Granath F; Sommar P
Article: BJS-BRITISH JOURNAL OF SURGERY. 2022;109(11):1107-1115
Long-term outcomes of implant-based immediate breast reconstruction with and without radiotherapy: a population-based study
de Boniface J; Adam HC; Frisell A; Oikonomou I; Ansarei D; Konstantinidou AL; Liu Y; Alniaj BA; Wallmon P; Halle M; Johansson ALV; Sackey H
Article: BREAST. 2022;63:16-23
Patient-reported outcomes one year after positive sentinel lymph node biopsy with or without axillary lymph node dissection in the randomized SENOMAC trial
Appelgren M; Sackey H; Wengstrom Y; Johansson K; Ahlgren J; Andersson Y; Bergkvist L; Frisell J; Lundstedt D; Ryden L; Sund M; Alkner S; Offersen BV; Tvedskov TF; Christiansen P; de Boniface J
Article: LAKARTIDNINGEN. 2022;119:21223
[Filler injection for breast augmentation - potentially harmful injections].
Hedström K; Sackey H; Falk Delgado A
Article: CHIRURGIA (BUCHAREST, ROMANIA : 1990). 2021;116(5):S128-S135
Local Recurrence after Treatment of Ductal Carcinoma In Situ: A Comprehensive Overview
Chiorescu A; Fredholm H; Sackey HI; Fredriksson I
Article: CHIRURGIA (BUCHAREST, ROMANIA : 1990). 2021;116(5):S7-S14
The Natural History of Ductal Carcinoma In Situ of the Breast - An Overview
Fredholm H; Chiorescu A; Fredriksson I; Sackey H
Article: BJS-BRITISH JOURNAL OF SURGERY. 2021;108(12):1474-1482
Effect of radiotherapy on expanders and permanent implants in immediate breast reconstruction: long-term surgical and patient-reported outcomes in a large multicentre cohort
Adam HC; Frisell A; Liu Y; Sackey H; Oikonomou I; Skogh A-CD; Frisell J; de Boniface J
Article: BJS OPEN. 2021;5(1):zraa013
Recurrence and survival after standard versus oncoplastic breast-conserving surgery for breast cancer
Andre C; Holsti C; Svenner A; Sackey H; Oikonomou I; Appelgren M; Johansson ALV; de Boniface J
Journal article: EUROPEAN JOURNAL OF CANCER. 2020;138:s28-s29
134 Poster Oncoplastic breast-conserving surgery offers low local recurrence rates and excellent survival rates despite worse tumor characteristics
André C; Holsti C; Svenner A; Oikonomou I; Sackey HI; Appelgren M; Johansson A; de Boniface J
Article: PSYCHO-ONCOLOGY. 2018;27(6):1615-1621
Sense of coherence is a predictor of survival: A prospective study in women treated for breast cancer
Lindblad C; Langius-Eklof A; Petersson L-M; Sackey H; Bottai M; Sandelin K
Article: LAKARTIDNINGEN. 2017;114:EDWR
[The road to breast conserving surgery and away from axillary dissection].
Bergkvist L; Frisell J; Sackey H
Article: BREAST CANCER RESEARCH. 2016;18(1):105
The impact of in situ breast cancer and family history on risk of subsequent breast cancer events and mortality - a population-based study from Sweden
Sackey H; Hui M; Czene K; Verkooijen H; Edgren G; Frisell J; Hartman M
Article: EJSO. 2015;41(4):577-584
Self-perceived, but not objective lymphoedema is associated with decreased long-term health-related quality of life after breast cancer surgery
Sackey H; Johansson H; Sandelin K; Liljegren G; MacLean G; Frisell J; Brandberg Y
Article: BJS-BRITISH JOURNAL OF SURGERY. 2014;101(4):390-397
Arm lymphoedema after axillary surgery in women with invasive breast cancer
Sackey H; Magnuson A; Sandelin K; Liljegren G; Bergkvist L; Fulep Z; Celebioglu F; Frisell J
Journal article: EJSO. 2012;38(9):737
16. Objective and subjective arm lymphedema after axillary surgery – A prospective multicenter study
Sackey H; Magnusson A; Fulep Z; Celebioglu F; Liljegren G; Sandelin K; Frisell J
Article: EJSO. 2010;36(8):756-762
Ductal carcinoma in situ of the breast. Long-term follow-up of health-related quality of life, emotional reactions and body image
Sackey H; Sandelin K; Frisell J; Wickman M; Brandberg Y
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All other publications

Review: SCANDINAVIAN JOURNAL OF SURGERY. 2025;:14574969251371888
Gender-affirming genital surgery in the Nordic countries: Narrative review of current practices and challenges
Mikkola A; Gran I; Sollie M; Holmgaard R; Ojala K; Sigurjonsson H; Bai L; Sackey H; Sommar P; Lofgren J
Review: SCANDINAVIAN JOURNAL OF SURGERY. 2025;:14574969251376097
Current practices and perspectives on gender-affirming breast and chest wall surgery in the Nordic region: An overview
Gran I; Mikkola A; Sollie M; Holmgaard R; Ojala K; Sigurjonsson H; Amoroso M; Sommar P; Frisen L; Lofgren J; Sackey H
Review: SCANDINAVIAN JOURNAL OF SURGERY. 2025;:14574969251371862
Gender-affirming healthcare in the Nordic countries: An overview
Gran I; Dhejne C; Mikkola A; Sollie M; Sommar P; Holmgaard R; Ojala K; Sigurjonsson H; Frisen L; Lofgren J; Sackey H
Conference publication: EUROPEAN JOURNAL OF CANCER. 2020;138:S28-S29
Oncoplastic breast-conserving surgery offers low local recurrence rates and excellent survival rates despite worse tumor characteristics
Andre C; Holsti C; Svenner A; Oikonomou I; Sackey HI; Appelgren M; Johansson A; de Boniface J
Meeting abstract: CANCER RESEARCH. 2012;72:p3-07-03-p3-07-03
The impact of Carcinoma in situ of the breast and family history on risk of subsequent breast cancer events and mortality - a population based study from Sweden
Sackey H; Hui M; Czene K; Edgren G; Frisell J; Hartman M
Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2011;47:S233
Sense of Coherence (SOC) is Stabile up to 3 Years Postoperatively - a Longitudinal Prospective Study in Women Surgically Treated for Breast Cancer
Lindblad C; Langius-Eklof A; Sackey H; Celebioglu F; Frisell J; Sandelin K

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2026-2028

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2014
University Medical Degree, Karolinska Institutet, 1999

Supervision

Supervision to doctoral degree
- Antti Mikkola, Gender affirming surgery – Surgical techniques and patient related outcomes, 2025-
- Matilda Appelgren, De-escalation of axillary surgery in breast cancer: patient experiences, arm morbidity, and health-related quality of life., 2025
- Karin Hedström, Seroma after mastectomy for breast cancer. Incidence, Prevention, and Health-Related Quality of Lif, 2024-
- Gran Isak, Patient reported outcomes after gender-affirming mastectomy, 2023-
- Yihang Liu, Postoperative complications after reconstructive breast surgery: incidence, consequences and association with oncological outcomes, 2022-
- Sars Carl, Sarcomas of the breast: an epidemiological and clinical investigation, 2021-
- Kamali Alexander, Outcome and aspects on transgender breast surgery, 2017-
Supervision of postdoctoral researcher
- Katarina Blom, 2025-

Articles

All other publications

Employments

Degrees and Education

Supervision

Supervision to doctoral degree

Supervision of postdoctoral researcher

News from KI

Events from KI