Staffan Strömblad

Staffan Strömblad

Professor
Telephone: +46852481122
Visiting address: Blickagången 16, 14152 Flemingsberg
Postal address: H7 Medicin, Huddinge, H7 ICCA Strömblad, 171 77 Stockholm
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About me

  • I am professor and group leader at the Department of Medicine Huddinge since 2024. Before this, I was professor at the Department of Biosciences and nutrition at KI since 2009. I obtained my basic univeristy degree at University of Stockholm in 1988 after studies in Biochemistry and Microbiology, and a PhD at Karolinska Institutet in 1992 in Experimental Pathology. After postdoctoral training at The Scripps Research Institute, La Jolla, CA, USA during 1994-96, I joined KI to form my own research group and have since then studied various aspects of cell-matrix interactions. I serve as the Scientific Director of the Live Cell Imaging Core Facility at KI and as a Member of the Nobel Assembly at KI. 

    My scientific philosophy:
    To describe my scientific philosophy, I am borrowing a quote from popular culture:

       “There is a crack - a crack in everything - that’s how the light comes in”
                  (from the song “Anthem” by Leonard Cohen)


    In every scientific dogma and prevailing view, there are cracks and gaps. If we can identify these cracks and find ways to observe the light coming     through, we have the possibility to gain fundamental new knowledge.

Research

  • Research interest areas:

    Cancer Cell Biology
    Cell-matrix interactions
    Mechanotransduction
    Cellular signaling
    Breast Cancer
    Cellular senescence

    For more information, please see my research group's home page

Articles

All other publications

Grants

  • Cell-matrix interactions in cancer
    Swedish Research Council
    1 January 2026 - 1 January 2029
  • Which pre-invasive tumors should be treated?
    Radiumhemmets Research Funds
    1 January 2025 - 1 January 2027
  • Cell-matrix interactions in cancer
    Swedish Cancer Society
    1 January 2024 - 1 January 2026
  • European Commission
    1 December 2023 - 31 August 2027
    Swept lasers have enabled paradigm-shifts in biomedical imaging and diagnostics. The SWEEPICS project will research and develop the next generation of swept source lasers with flexible pulse modulation capability, high power output, multi-wavelength coherent output and multi-application potential. SWEEPICS will develop new laser-based systems: a high-speed, high resolution multiphoton high content screening system, a multimodal non-invasive imaging system based on high-speed photoacoustics and multiphoton microscopy, and a smart microscope for accelerated acquisition&diagnostics. The inter-disciplinary consortium of European partners will showcase the SWEEPICS technology in cutting-edge use cases based on novel vascular organoids for animal-free drug-testing and infection studies. This disruptive SWEEPICS technology will rapidly generate high-resolution diagnostic imaging in three-dimension, where the high imaging depth permits penetrating millimeter deep into tissue-like organoids and imaging at high temporal and spatial resolution in order to allow for a drastic reduction of animal testing and increased speed of diagnostic results. It will allow the study of dynamic processes in real-time and at multiple length scales, enabling researchers to observe how cells and tissues respond to viral infections or pathogen-induced inflammation, while also permitting a high-throughput enabled discovery of novel diagnostic biomarkers. Overall, this technology represents a major breakthrough in capable laser technology for high accuracy and throughput medical diagnostics and is poised to make significant contributions to the European laser and biomedical technology landscape.

Employments

  • Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
  • Professor, Department of Biosciences and Nutrition, Karolinska Institutet, 2009-2024

Degrees and Education

  • Docent, Karolinska Institutet, 2000

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