Sonia Lain
Professor Emeritus
E-postadress: sonia.lain@ki.se
Besöksadress: Solnavägen 9, B7, 17165 Solna
Postadress: C1 Mikrobiologi, tumör- och cellbiologi, C1 Tumor Biology Wilhelm, 171 77 Stockholm
Del av:
- Institutionen för mikrobiologi, tumör- och cellbiologi
- Avdelningen för tumörbiologi
- Wilhelm lab
Om mig
- Sonia Lain letar efter molekyler som kan utvecklas till framtida cancerbehandlingar. Ur mer än 60 000 substanser har hon valt ut de mest lovande kandidaterna. Efter att de molekylära mekanismerna kartlagts går det också att se vilka andra sjukdomar som substanserna kan vara effektiva mot.
Artiklar
- Article: HELIYON. 2024;10(1):e23831Mollick T; Darekar S; Dalarun B; Plastino F; Zhang J; Fernandez AP; Alkasalias T; Andre H; Lain S
- Article: BIOESSAYS. 2022;44(12):e2200128Darekar S; Lain S
- Article: CELL DEATH DISCOVERY. 2022;8(1):464Alkasalias T; Zhang J; Madapura H; Dalarun B; Reina OB; Lewensohn R; Viktorsson K; Salihi A; Darekar S; Lain S
- Article: ISCIENCE. 2021;24(5):102494Zhang J; Teran G; Popa M; Madapura H; Ladds MJGW; Lianoudaki D; Grunler J; Arsenian-Henriksson M; McCormack E; Rottenberg ME; Catrina S-B; Lain S; Darekar S
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(52):17935-17949Ladds MJGW; Popova G; Pastor-Fernandez A; Kannan S; van Leeuwen IMM; Hakansson M; Walse B; Tholander F; Bhatia R; Verma CS; Lane DP; Lain S
- Article: FEBS JOURNAL. 2020;287(13):2823-2833Kaldmae M; Leppert A; Chen G; Sarr M; Sahin C; Nordling K; Kronqvist N; Gonzalvo-Ulla M; Fritz N; Abelein A; Lain S; Biverstal H; Jornvall H; Lane DP; Rising A; Johansson J; Landreh M
- Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(8):3915-3934Popova G; Ladds MJGW; Johansson L; Saleh A; Larsson J; Sandberg L; Sahlberg SH; Qian W; Gullberg H; Garg N; Gustavsson A-L; Haraldsson M; Lane D; Yngve U; Lain S
- Article: CLINICAL GENETICS. 2019;96(3):216-225Kharaziha P; Ceder S; Axell O; Krall M; Fotouhi O; Bohm S; Lain S; Borg A; Larsson C; Wiman KG; Tham E; Bajalica-Lagercrantz S
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(9):4115-4131Keszei M; Record J; Kritikou JS; Wurzer H; Geyer C; Thiemann M; Drescher P; Brauner H; Kocher L; James J; He M; Baptista MAP; Dahlberg CIM; Biswas A; Lain S; Lane DP; Song W; Putsep K; Vandenberghe P; Snapper SB; Westerberg LS
- Article: JOURNAL OF PHYSICAL CHEMISTRY LETTERS. 2018;9(14):4082-4086Gault J; Lianoudaki D; Kaldmae M; Kronqvist N; Rising A; Johansson J; Lohkamp B; Lain S; Allison TM; Lane DP; Marklund EG; Landreh M
- Article: PLOS ONE. 2018;13(4):e0195956Ladds MJGW; Pastor-Fernandez A; Popova G; van Leeuwen IMM; Eng KE; Drummond CJ; Johansson L; Svensson R; Westwood NJ; McCarthy AR; Tholander F; Popa M; Lane DP; McCormack E; McInerney GM; Bhatia R; Lain S
- Article: NATURE COMMUNICATIONS. 2018;9(1):1107Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
- Article: CELL CHEMICAL BIOLOGY. 2018;25(3):309-317.e4Costeira-Paulo J; Gault J; Popova G; Ladds MJGW; van Leeuwen IMM; Sarr M; Olsson A; Lane DP; Lain S; Marklund EG; Landreh M
- Article: CELL CYCLE. 2016;15(9):1267-1275Madapura HS; Salamon D; Wiman KG; Lain S; Klein E; Nagy N
- Article: ONCOTARGET. 2015;6(18):16488-16506Sachweh MCC; Stafford WC; Drummond CJ; McCarthy AR; Higgins M; Campbell J; Brodin B; Arner ESJ; Lain S
- Article: NATURE BIOTECHNOLOGY. 2015;33(4):415-423Scholz C; Weinert BT; Wagner SA; Beli P; Miyake Y; Qi J; Jensen LJ; Streicher W; McCarthy AR; Westwood NJ; Lain S; Cox J; Matthias P; Mann M; Bradner JE; Choudhary C
- Article: CELL DEATH & DISEASE. 2014;5(10):e1483Ma L; Maruwge W; Strambi A; D'Arcy P; Pellegrini P; Kis L; de Milito A; Lain S; Brodin B
- Article: CELL STEM CELL. 2014;15(4):431-446Li L; Osdal T; Ho Y; Chun S; McDonald T; Agarwal P; Lin A; Chu S; Qi J; Li L; Hsieh Y-T; Dos Santos C; Yuan H; Ha T-Q; Popa M; Hovland R; Bruserud O; Gjertsen BT; Kuo Y-H; Chen W; Lain S; McCormack E; Bhatia R
- Article: MOLECULAR CANCER. 2014;13:116Haaland I; Opsahl JA; Berven FS; Reikvam H; Fredly HK; Haugse R; Thiede B; McCormack E; Lain S; Bruserud O; Gjertsen BT
- Article: MOLECULAR CANCER THERAPEUTICS. 2013;12(4):352-360McCarthy AR; Sachweh MCC; Higgins M; Campbell J; Drummond CJ; van Leeuwen IMM; Pirrie L; Ladds MJGW; Westwood NJ; Lain S
- Article: MOLECULAR CANCER THERAPEUTICS. 2013;12(4):471-480van Leeuwen IMM; Higgins M; Campbell J; McCarthy AR; Sachweh MCC; Navarro AM; Lain S
- Article: CELL DEATH & DISEASE. 2013;4(3):e533Sachweh MCC; Drummond CJ; Higgins M; Campbell J; Lain S
- Article: SCIENTIFIC REPORTS. 2013;3:1275MacCallum SF; Groves MJ; James J; Murray K; Appleyard V; Prescott AR; Drbal AA; Nicolaou A; Cunningham J; Haydock S; Ganley IG; Westwood NJ; Coates PJ; Lain S; Tauro S
- Article: CELL CYCLE. 2012;11(24):4563-4569Madapura HS; Salamon D; Wiman KG; Lain S; Klein G; Klein E; Nagy N
- Article: CELL CYCLE. 2012;11(9):1851-1861van Leeuwen IMM; Rao B; Sachweh MCC; Lain S
- Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2012;20(5):1779-1793McCarthy AR; Pirrie L; Hollick JJ; Ronseaux S; Campbell J; Higgins M; Staples OD; Fanny T; Slawin AMZ; Lain S; Westwood NJ
- Article: RSC MEDICINAL CHEMISTRY. 2011;2(7):611-615Medda F; Joseph TL; Pirrie L; Higgins M; Slawin AMZ; Lain S; Verma C; Westwood NJ
- Article: CELL CYCLE. 2011;10(10):1590-1598van Leeuwen IMM; Higgins M; Campbell J; Brown CJ; McCarthy AR; Pirrie L; Westwood NJ; Lain S
- Article: ONCOTARGET. 2010;1(7):639-650Rao B; van Leeuwen IMM; Higgins M; Campbell J; Thompson AM; Lane DP; Lain S
- Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2010;2(9):a001222Lane DP; Cheok CF; Lain S
- Article: DNA REPAIR. 2009;8(10):1215-1224Yadavilli S; Mayo LD; Higgins M; Lain S; Hegde V; Deutsch WA
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2009;35(3):649-656Jolly CE; Gray LJ; Parish JL; Lain S; Herrington CS
- Article: JOURNAL OF MEDICINAL CHEMISTRY. 2009;52(9):2673-2682Medda F; Russell RJM; Higgins M; McCarthy AR; Campbell J; Slawin AMZ; Lane DP; Lain S; Westwood NJ
- Article: CELL CYCLE. 2008;7(21):3417-3427Staples OD; Hollick JJ; Campbell J; Higgins M; McCarthy AR; Appleyard V; Murray KE; Baker L; Thompson A; Ronseaux S; Slawin AMZ; Lane DP; Westwood NJ; Lain S
- Article: CANCER CELL. 2008;13(5):454-463Lain S; Hollick JJ; Campbell J; Staples OD; Higgins M; Aoubala M; McCarthy A; Appleyard V; Murray KE; Baker L; Thompson A; Mathers J; Holland SJ; Stark MJR; Pass G; Woods J; Lane DP; Westwood NJ
- Article: ONCOGENE. 2007;26(28):4059-4070Camus S; Menendez S; Cheok CF; Stevenson LF; Lain S; Lane DP
- Article: INTERNATIONAL JOURNAL OF CANCER. 2007;120(11):2317-2324Gray LJ; Bjelogrlic P; Appleyard VCL; Thompson AM; Jolly CE; Lain S; Herrington CS
- Article: INTERNATIONAL JOURNAL OF CANCER. 2005;115(5):701-710Berkson RG; Hollick JJ; Westwood NJ; Woods JA; Lane DP; Lain S
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(21):18720-18729Menéndez S; Khan Z; Coomber DW; Lane DP; Higgins M; Koufali MM; Laín S
- Article: BRITISH JOURNAL OF CANCER. 2003;88(4):636-643Menéndez S; Higgins M; Berkson RG; Edling C; Lane DP; Laín S
- Article: FEBS LETTERS. 2003;536(1-3):220-224Camus S; Higgins M; Lane DP; Lain S
- Article: ONCOGENE. 2001;20(36):4972-4983Xirodimas D; Saville MK; Edling C; Lane DP; Laín S
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(22):19469-19482Sapkota GP; Kieloch A; Lizcano JM; Lain S; Arthur JSC; Williams MR; Morrice N; Deak M; Alessi DR
- Article: MOLECULAR CARCINOGENESIS. 2000;29(4):251-262Paramio JM; Segrelles C; Laín S; Gómez-Casero E; Lane DP; Lane EB; Jorcano JL
- Article: MOLECULAR AND CELLULAR BIOLOGY. 2000;20(22):8458-8467Rodriguez MS; Desterro JMP; Lain S; Lane DP; Hay RT
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(15):8501-8506Hietanen S; Lain S; Krausz E; Blattner C; Lane DP
- Article: ONCOGENE. 1999;18(51):7378-7386Smart P; Lane EB; Lane DP; Midgley C; Vojtesek B; Laín S
- Article: EMBO JOURNAL. 1999;18(22):6455-6461Rodriguez MS; Desterro JMP; Lain S; Midgley CA; Lane DP; Hay RT
- Article: EXPERIMENTAL CELL RESEARCH. 1999;248(2):457-472Laín S; Midgley C; Sparks A; Lane EB; Lane DP
- Article: ONCOGENE. 1998;17(8):949-957Paramio JM; Laín S; Segrelles C; Lane EB; Jorcano JL
- Article: ONCOGENE. 1998;16(5):587-596Fåhraeus R; Laín S; Ball KL; Lane DP
- Article: CURRENT BIOLOGY. 1997;7(1):71-80Ball KL; Lain S; Fahraeus R; Smythe C; Lane DP
- Article: CURRENT BIOLOGY. 1996;6(1):84-91Fahraeus R; Paramio JM; Ball KL; Lain S; Lane DP
- Article: JOURNAL OF GENERAL VIROLOGY. 1995;76:2679-2692SJOBLOM A; JANSSON A; YANG WW; LAIN S; NILSSON T; RYMO L
- Article: NUCLEIC ACIDS RESEARCH. 1995;23(8):1327-1332FERNANDEZ A; LAIN S; GARCIA JA
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Alla övriga publikationer
- Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):5019Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Faernegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
- Review: CANCER & METABOLISM. 2020;8(1):12Mollick T; Lain S
- Review: JOURNAL OF MOLECULAR CELL BIOLOGY. 2019;11(3):245-254Ladds MJGW; Lain S
- Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
- Review: BRITISH JOURNAL OF CANCER. 2013;109(12):2954-2958Rao B; Lain S; Thompson AM
- Editorial: ONCOTARGET. 2011;2(4):274-276van Leeuwen IMM; Lain S
- Review: NATURE REVIEWS CANCER. 2009;9(12):862-873Brown CJ; Lain S; Verma CS; Fersht AR; Lane DP
- Review: MECHANISMS AND THERAPY OF LIVER CANCER. 2009;102:171-195van Leeuwen I; Lain S
- Review: SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND. 2008;6(4):240-243Staples OD; Steele RJC; Lain S
- Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2006;4(12):75Lane D; Lain S
- Review: BRITISH JOURNAL OF CANCER. 2005;92(3):434-444Munro AJ; Lain S; Lane DP
- Review: EUROPEAN JOURNAL OF CANCER. 2003;39(8):1053-1060Lain S; Lane D
- Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2003;31(2):482-485Lain S
- Review: TRENDS IN MOLECULAR MEDICINE. 2002;8(4):S38-S42Lane DP; Lain S
- Review: EXPERIMENTAL CELL RESEARCH. 1999;253(2):315-324Laín S; Xirodimas D; Lane DP
Anställningar
- Professor Emeritus, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2026-2028
- Professor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2015-2025
Examina och utbildning
- Docent, Tumörbiologi, Karolinska Institutet, 2012