SOSVASC – David Lindström's research group

The SOSVASC group focuse on vascular disorders such as aortic aneurysms, aortic dissections, carotid stenosis, peripheral arterial disease, thoracic outlet syndromes. We also have a research focus on wounds, trauma and vascular nursing.

Part of the:

Vascular Surgery Research Group KI SÖS

To strengthen the clinical research at KI SÖS we have broadened ongoing projects by networking with other groups at Karolinska Institutet, as well as national and international external departments. The SOSVASC group is the connective link for persons involved in vascular research.

  • Carotid disease
  • Peripheral artery disease (PAD)
  • Aortic disease
  • Trauma
  • Caring science
  • Wound therapy

Publications

All publications from group members

  • Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2026;113(3):znag008
    Jonsson G; Mani K; Wanhainen A; Lindström D
  • Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2026;:S1078-5884(26)00135-8
    Dean A; Feng K; Hassan S; Marzoug A; Lindstrom D; Holden A
  • Article: JOURNAL OF ENDOVASCULAR THERAPY. 2026;33(1):397-405
    Shehab M; Wanhainen A; Tegler G; Lindstrom D; Yoon W; Mani K
  • Article: ANNALS OF VASCULAR SURGERY. 2026;123:608-616
    Lindberg M; Gillgren P; Gunnarsson K; Kragsterman B; Lindstro D; Roy J; Wanhainen A; Jonsson M
  • Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2026;71(1):157
    Mill V; Steuer J
  • Letter: ANNALS OF VASCULAR SURGERY. 2025;121:613-615
    Sartipy F; Schalling KM; Mill V; Gillgren P; Malmstedt J
  • Journal article: BMC INFECTIOUS DISEASES. 2025;25(1):1681
    Fritzell V; Dwyer R; Lindstrom D
  • Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2025;:S1078-5884(25)01190-6
    Mill V; Malmstedt J; Gillgren P; Lindström D
  • Article: NURSING IN CRITICAL CARE. 2025;30(6):e70251
    Nyberg PK; Gunther M; Fagerdahl A; Alga A
  • Journal article: ANZ JOURNAL OF SURGERY. 2025;95(10):2039-2045
    Beaumont M; Hobson K; Rax H; Sutton A; Hill A; Lindstrom D; Dean A
  • Journal article: JOURNAL OF ENDOVASCULAR THERAPY. 2025;32(5):1641-1646
    Jonsson GG; Shehab M; Wanhainen A; Mani K; Kuzniar M; Lindstrom D
  • Review: JOURNAL OF CARDIOVASCULAR SURGERY. 2025;66(5):405-415
    Rahman T; Bicknell CD; Mussa FF; Bjorkman P
  • Article: LANCET. 2025;406(10508):1103-1114
    Falkenberg M; James S; Andersson M; Andersson M; Delle M; Engstrom J; Fransson T; Gillgren P; Hilbertson A; Horer TM; Jacobsson E; Kragsterman B; Lindback J; Lindgren H; Ludwigs K; Mellander S; Nelzen O; Olin R; Sigvant B; Skoog P; Starck J; Tegler G; Thorbjornsen K; Truedson M; Wahlgren C-M; Wallinder J; Ojersjo A; Nordanstig J
  • Article: LANCET. 2025;406(10508):1115-1127
    Nordanstig J; James S; Andersson M; Andersson M; Delle M; Engstrom J; Fransson T; Gillgren P; Hilbertson A; Horer TM; Jacobsson E; Kragsterman B; Lindback J; Lindgren H; Ludwigs K; Mellander S; Nelzen O; Olin R; Sigvant B; Skoog P; Starck J; Tegler G; Thorbjornsen K; Truedson M; Wahlgren C-M; Wallinder J; Ojersjo A; Falkenberg M
  • Conference publication: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:xi25
    Jonsson G; Mani K; Wanhainen A; Lindstrom D
  • Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.011-xi3
    Holtenius F; Gunther M; Alga A
  • Journal article: BJS-BRITISH JOURNAL OF SURGERY. 2025;112:znaf149.091-xi26
    Schalling K; Sartipy F; Gillgren P; Lindstrom D; Mill V; Smedberg C; Westerlund E; Malmstedt J
  • Article: BMC NURSING. 2025;24(1):855
    von Vogelsang A-C; Falk-Brynhildsen K; Erestam S; Swenne CL; Torbjornsson E
  • Article: ANNALS OF VASCULAR SURGERY. 2025;116:103-108
    Dean A; Hassan S; Yoon W; Mani K; Wanhainen A; Lindstrom D
  • Article: JOURNAL OF HOSPITAL INFECTION. 2025;161:13-18
    Torbjornsson E; Olivecrona C; Ngo AL; Tammelin A
  • Show more

Staff and contact

Group leader

All members of the group

Research

Projects

Carotid disease

  1. Methodological aspects on carotid intervention.
  2. Biomarkers and cellular mechanisms to predict unstable arterioscleroses.

Aortic disease

  1. Aneurysm of the abdominal aorta; hereditary aspects and screening.
  2. Ruptured abdominal aortic aneurysm – patient characteristics, x-ray findings and results of treatment.
  3. Mapping of the prevalence and treatment results of aortic dissection.
  4. The results of treatment when branched endovascular grafts are used involving visceral arteries.

Peripheral artery disease (PAD)

  1. PAD and diabetes; mechanisms for ischemia and long term results.
  2. The natural course for patients with PAD.
  3. Risk factors for worsened outcome after amputation preceded by a vascular intervention.
  4. Evaluation of patient centered follow-up program after vascular intervention for claudication.

Trauma

  1. Long term follow-up for patients treated for traumatic aortic injury.
  2. Evaluation and improvement of surgical methods in blast and gun wounds.

National and international studies

  • ACST-2: Asymptomatic Carotid Surgery Trial. Large international randomized trial comparing carotid endarterectomy vs. carotid artery stenting in patients with asymptomatic carotid stenosis. Peter Gillgren is principal investigator in Sweden. Website.
  • Swedpad study: National Swedish randomized study comparing balloons and stents with – and without – drug eluting mechanism for patients with PAD.
  • Basil-2 study: A multi-centre randomised controlled trial to find out if a ‘vein bypass first’ or a ‘best endovascular first’ revascularisation strategy is best in patients with severe limb ischaemia. Website.

Articles that have changed the clinical routines in our patients

  • We have shown that urgent treatment of symptomatic carotid stenting is not associated with an increased risk as compared to later stenting 1
  • In a collaboration with the University hospital in Zurich, Dr Steuer has shown that there is a sub-acute phase in type B aortic dissection 2
  • In a collaboration with the STAR group (name as link) at the Institution of molecular medicine and surgery along with Dr Linné, the SOSVASC group has shown the link between low income, low educational level and immigrant status and non-participating in aortic screening programmes. In addition Dr Linné has shown that results of treatment do not vary between screened and non-screened patients with aortic abdominal aneurysms. 3
  • Dr Sartipy has shown that procalcitonin is a valuable marker when distinguishing infection from inflammation after endovascular treatment for abdominal aneurysms. 4
  • An increase of the marker PCSK6, a protease, is seen in patients with unstable arteriosclerosis. 5

Collaborations

Keywords:
Aortic Aneurysm Aortic Dissection Cardiology and Cardiovascular Disease Carotid Stenosis Dissection, Thoracic Aorta Show all
Content reviewer:
David Lindström
13-03-2026